Jacob Smith
Contact Information
Job Title
Advisor: Vladislav Belyy
Areas of Expertise
- Chemistry & Biochemistry
Education
- BS, Biochemistry, The Ohio State University, 2021
Publications
- Smith JW, Wilburn DB, Belyy V. Direct optical activation of human IRE1 identifies unique patterns of transcriptional and post-transcriptional mRNA regulation in the unfolded protein response. J Biol Chem. 2026 Feb;302(2):111067. doi: 10.1016/j.jbc.2025.111067. Epub 2025 Dec 18. PMID: 41421490; PMCID: PMC12858354.
- Smith JW, Wilburn DB, Belyy V. Optogenetic Clustering of Human IRE1 Reveals Differential Regulation of Transcription and mRNA Splice Isoform Abundance by the UPR. bioRxiv [Preprint]. 2025 Jul 21:2025.07.16.665212. doi: 10.1101/2025.07.16.665212. PMID: 40777275; PMCID: PMC12330662.